siRNA, Anti-ISCA1, 2'-F/2'-OMe/2'-MOE/Backbone-modified(CAT#: SIRGT66973WQ-2OMe)

The product SIRGT66973WQ-2OMe is a type of small interfering RNA (siRNA) that targets ISCA1 gene and regulates the expression of gene. The siRNA interferes with the expression of ISCA1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_030940.3
Alternative Names HBLD2; ISA1; MMDS5; hIscA
Related Diseases Multiple Mitochondrial Dysfunctions Syndrome 5
Purification HPLC
Target Gene
Gene ID 81689
Uniprot ID Q9BUE6
Sub Cat Target Species Modification Scale  
SIRGT67973WQ-2F ISCA1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT68973WQ-2MOE ISCA1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT67973WQ-BB ISCA1 Human Backbone-modified Inquiry

Related Products