siRNA, Anti-ISX, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51467WQ-2OMe)

The product SIRGT51467WQ-2OMe is a type of small interfering RNA (siRNA) that targets ISX gene and regulates the expression of gene. The siRNA interferes with the expression of ISX gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001303508.1
Alternative Names Pix-1; RAXLX
Related Diseases Trichohepatoenteric Syndrome 1
Purification HPLC
Target Gene
Gene ID 91464
Uniprot ID Q2M1V0
Sub Cat Target Species Modification Scale  
SIRGT52467WQ-2F ISX Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53467WQ-2MOE ISX Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54467WQ-LNA ISX Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51467WQ-RB ISX Human Ribo-modified Inquiry
SIRGT52467WQ-BB ISX Human Backbone-modified Inquiry

Related Products