siRNA, Anti-IZUMO1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT66851WQ-2OMe)

The product SIRGT66851WQ-2OMe is a type of small interfering RNA (siRNA) that targets IZUMO1 gene and regulates the expression of gene. The siRNA interferes with the expression of IZUMO1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001321864.1
Alternative Names IZUMO; OBF
Related Diseases Glaucoma
Purification HPLC
Target Gene
Gene ID 284359
Uniprot ID Q8IYV9
Sub Cat Target Species Modification Scale  
SIRGT67851WQ-2F IZUMO1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT68851WQ-2MOE IZUMO1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT69851WQ-LNA IZUMO1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT66851WQ-RB IZUMO1 Human Ribo-modified Inquiry
SIRGT67851WQ-BB IZUMO1 Human Backbone-modified Inquiry

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