siRNA, Anti-KIAA1755, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51244WQ-2OMe)

The product SIRGT51244WQ-2OMe is a type of small interfering RNA (siRNA) that targets KIAA1755 gene and regulates the expression of gene. The siRNA interferes with the expression of KIAA1755 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001029864.1
Related Diseases Meckel Syndrome, Type 1
Purification HPLC
Target Gene
Gene ID 85449
Uniprot ID Q5JYT7
Sub Cat Target Species Modification Scale  
SIRGT52244WQ-2F KIAA1755 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53244WQ-2MOE KIAA1755 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54244WQ-LNA KIAA1755 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51244WQ-RB KIAA1755 Human Ribo-modified Inquiry
SIRGT52244WQ-BB KIAA1755 Human Backbone-modified Inquiry

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