siRNA, Anti-KLHL40, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT56278WQ-2OMe)

The product SIRGT56278WQ-2OMe is a type of small interfering RNA (siRNA) that targets KLHL40 gene and regulates the expression of gene. The siRNA interferes with the expression of KLHL40 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_152393.3
Alternative Names KBTBD5; NEM8; SRYP; SYRP
Related Diseases Nemaline Myopathy 8
Purification HPLC
Target Gene
Gene ID 131377
Uniprot ID Q2TBA0
Sub Cat Target Species Modification Scale  
SIRGT57278WQ-2F KLHL40 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT58278WQ-2MOE KLHL40 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT59278WQ-LNA KLHL40 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT56278WQ-RB KLHL40 Human Ribo-modified Inquiry
SIRGT57278WQ-BB KLHL40 Human Backbone-modified Inquiry

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