siRNA, Anti-KNSTRN, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51370WQ-2OMe)

The product SIRGT51370WQ-2OMe is a type of small interfering RNA (siRNA) that targets KNSTRN gene and regulates the expression of gene. The siRNA interferes with the expression of KNSTRN gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001142761.1
Alternative Names C15orf23; HSD11; SKAP; TRAF4AF1
Related Diseases Roifman-Chitayat Syndrome
Purification HPLC
Target Gene
Gene ID 90417
Uniprot ID Q9Y448
Sub Cat Target Species Modification Scale  
SIRGT52370WQ-2F KNSTRN Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53370WQ-2MOE KNSTRN Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54370WQ-LNA KNSTRN Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51370WQ-RB KNSTRN Human Ribo-modified Inquiry
SIRGT52370WQ-BB KNSTRN Human Backbone-modified Inquiry

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