siRNA, Anti-KRTAP1-1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT71427WQ-2OMe)
The product SIRGT71427WQ-2OMe is a type of small interfering RNA (siRNA) that targets KRTAP1-1 gene and regulates the expression of gene. The siRNA interferes with the expression of KRTAP1-1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_030967.2 |
| Alternative Names | HB2A; KAP1.1; KAP1.1A; KAP1.1B; KAP1.6; KAP1.7; KRTAP1.1; KRTAP1A; hKAP1.7 |
| Related Diseases | Pulmonary Embolism And Infarction |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT72427WQ-2F | KRTAP1-1 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT73427WQ-2MOE | KRTAP1-1 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT74427WQ-LNA | KRTAP1-1 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT71427WQ-RB | KRTAP1-1 | Human | Ribo-modified | ||
| SIRGT72427WQ-BB | KRTAP1-1 | Human | Backbone-modified |
