siRNA, Anti-KRTAP27-1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT66574WQ-2OMe)
The product SIRGT66574WQ-2OMe is a type of small interfering RNA (siRNA) that targets KRTAP27-1 gene and regulates the expression of gene. The siRNA interferes with the expression of KRTAP27-1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001077711.1 |
| Related Diseases | Three M Syndrome 1 |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT67574WQ-2F | KRTAP27-1 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT68574WQ-2MOE | KRTAP27-1 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT69574WQ-LNA | KRTAP27-1 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT101137WQ-2OMe | Krtap27-1 | Mouse | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT103137WQ-2MOE | Krtap27-1 | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT104137WQ-LNA | Krtap27-1 | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT66574WQ-RB | KRTAP27-1 | Human | Ribo-modified | ||
| SIRGT101137WQ-RB | Krtap27-1 | Mouse | Ribo-modified | ||
| SIRGT102137WQ-BB | Krtap27-1 | Mouse | Backbone-modified |
