siRNA, Anti-KRTAP4-5, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51199WQ-2OMe)
The product SIRGT51199WQ-2OMe is a type of small interfering RNA (siRNA) that targets KRTAP4-5 gene and regulates the expression of gene. The siRNA interferes with the expression of KRTAP4-5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_033188.3 |
| Alternative Names | KAP4.5; KRTAP4.5 |
| Related Diseases | Hypopharynx Cancer |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT52199WQ-2F | KRTAP4-5 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT53199WQ-2MOE | KRTAP4-5 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT54199WQ-LNA | KRTAP4-5 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT51199WQ-RB | KRTAP4-5 | Human | Ribo-modified | ||
| SIRGT52199WQ-BB | KRTAP4-5 | Human | Backbone-modified |
