siRNA, Anti-LCN12, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT71452WQ-2OMe)

The product SIRGT71452WQ-2OMe is a type of small interfering RNA (siRNA) that targets LCN12 gene and regulates the expression of gene. The siRNA interferes with the expression of LCN12 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_178536.3
Related Diseases Corneal Ectasia
Purification HPLC
Target Gene
Gene ID 286256
Uniprot ID Q6JVE5
Sub Cat Target Species Modification Scale  
SIRGT72452WQ-2F LCN12 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT73452WQ-2MOE LCN12 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT74452WQ-LNA LCN12 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT71452WQ-RB LCN12 Human Ribo-modified Inquiry
SIRGT72452WQ-BB LCN12 Human Backbone-modified Inquiry

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