siRNA, Anti-LRP5L, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51454WQ-2OMe)

The product SIRGT51454WQ-2OMe is a type of small interfering RNA (siRNA) that targets LRP5L gene and regulates the expression of gene. The siRNA interferes with the expression of LRP5L gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001135772.1
Related Diseases Periodontosis
Purification HPLC
Target Gene
Gene ID 91355
Uniprot ID A4QPB2
Sub Cat Target Species Modification Scale  
SIRGT52454WQ-2F LRP5L Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53454WQ-2MOE LRP5L Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54454WQ-LNA LRP5L Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51454WQ-RB LRP5L Human Ribo-modified Inquiry
SIRGT52454WQ-BB LRP5L Human Backbone-modified Inquiry

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