siRNA, Anti-MAT2B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT77459WQ-2F)
The product SIRGT77459WQ-2F is a type of small interfering RNA (siRNA) that targets MAT2B gene and regulates the expression gene. The siRNA interferes with the expression MAT2B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_182796.2 |
| Alternative Names | MAT-II; MATIIbeta; Nbla02999; SDR23E1; TGR |
| Related Diseases | Hypermethioninemia |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT76459WQ-2OMe | MAT2B | Human | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT79459WQ-LNA | MAT2B | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT86099WQ-2OMe | Mat2b | Mouse | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT87099WQ-2F | Mat2b | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT88099WQ-2MOE | Mat2b | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT89099WQ-LNA | Mat2b | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT76459WQ-RB | MAT2B | Human | Ribo-modified | ||
| SIRGT86099WQ-RB | Mat2b | Mouse | Ribo-modified | ||
| SIRGT77459WQ-BB | MAT2B | Human | Backbone-modified |
