siRNA, Anti-METAP1D, 2'-OMe-modified(CAT#: SIRGT61784WQ-2OMe)
The product SIRGT61784WQ-2OMe is a type of small interfering RNA (siRNA) that targets METAP1D gene and regulates the expression of gene. The siRNA interferes with the expression of METAP1D gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| Modification | 2ʹ-O-methyl (2'-OMe) |
| Scale | 20/50/100/200 nmole |
| NCBI RefSeq | NM_001322278.1 |
| Alternative Names | MAP 1D; MAP1D; MetAP 1D; Metap1l |
| Related Diseases | Spinocerebellar Ataxia 28 |
| Purification | HPLC |