siRNA, Anti-METTL18, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51552WQ-2OMe)

The product SIRGT51552WQ-2OMe is a type of small interfering RNA (siRNA) that targets METTL18 gene and regulates the expression of gene. The siRNA interferes with the expression of METTL18 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001320199.1
Alternative Names AsTP2; C1orf156; HPM1
Related Diseases Combined Oxidative Phosphorylation Deficiency 3
Purification HPLC
Target Gene
Gene ID 92342
Uniprot ID O95568
Sub Cat Target Species Modification Scale  
SIRGT52552WQ-2F METTL18 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53552WQ-2MOE METTL18 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54552WQ-LNA METTL18 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51552WQ-RB METTL18 Human Ribo-modified Inquiry
SIRGT52552WQ-BB METTL18 Human Backbone-modified Inquiry

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