siRNA, Anti-METTL3, 2'-F/2'-OMe/LNA/Backbone-modified(CAT#: SIRGT71498WQ-2OMe)

The product SIRGT71498WQ-2OMe is a type of small interfering RNA (siRNA) that targets METTL3 gene and regulates the expression of gene. The siRNA interferes with the expression of METTL3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_019852.4
Alternative Names IME4; M6A; MT-A70; Spo8; hMETTL3
Related Diseases Miyoshi Muscular Dystrophy 3
Purification HPLC
Target Gene
Gene ID 56339
Uniprot ID Q86U44
Sub Cat Target Species Modification Scale  
SIRGT72498WQ-2F METTL3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT74498WQ-LNA METTL3 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT72498WQ-BB METTL3 Human Backbone-modified Inquiry

Related Products