siRNA, Anti-MRPL46, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT71337WQ-2OMe)

The product SIRGT71337WQ-2OMe is a type of small interfering RNA (siRNA) that targets MRPL46 gene and regulates the expression of gene. The siRNA interferes with the expression of MRPL46 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_022163.3
Alternative Names C15orf4; LIECG2; P2ECSL
Related Diseases Congenital Dyserythropoietic, Type Iii
Purification HPLC
Target Gene
Gene ID 26589
Uniprot ID Q9H2W6
Sub Cat Target Species Modification Scale  
SIRGT72337WQ-2F MRPL46 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT73337WQ-2MOE MRPL46 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT74337WQ-LNA MRPL46 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT71337WQ-RB MRPL46 Human Ribo-modified Inquiry
SIRGT72337WQ-BB MRPL46 Human Backbone-modified Inquiry

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