siRNA, Anti-MUC15, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT59526WQ-LNA)

The product SIRGT59526WQ-LNA is a type of small interfering RNA (siRNA) that targets MUC15 gene and regulates the expression of gene. The siRNA interferes with the expression of MUC15 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001135091.1
Alternative Names MUC-15; PAS3; PASIII
Related Diseases Tn Polyagglutination Syndrome
Purification HPLC
Target Gene
Gene ID 143662
Uniprot ID Q8N387
Sub Cat Target Species Modification Scale  
SIRGT56526WQ-2OMe MUC15 Human 2ʹ-O-methyl (2'-OMe) Inquiry
SIRGT57526WQ-2F MUC15 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT58526WQ-2MOE MUC15 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT56526WQ-RB MUC15 Human Ribo-modified Inquiry
SIRGT57526WQ-BB MUC15 Human Backbone-modified Inquiry

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