siRNA, Anti-NELFB, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT74069WQ-LNA)

The product SIRGT74069WQ-LNA is a type of small interfering RNA (siRNA) that targets NELFB gene and regulates the expression of gene. The siRNA interferes with the expression of NELFB gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_015456.4
Alternative Names COBRA1; NELF-B
Related Diseases Femoral Neuropathy
Purification HPLC
Target Gene
Gene ID 25920
Uniprot ID Q8WX92
Sub Cat Target Species Modification Scale  
SIRGT71069WQ-2OMe NELFB Human 2ʹ-O-methyl (2'-OMe) Inquiry
SIRGT72069WQ-2F NELFB Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT73069WQ-2MOE NELFB Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT71069WQ-RB NELFB Human Ribo-modified Inquiry
SIRGT72069WQ-BB NELFB Human Backbone-modified Inquiry

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