siRNA, Anti-NGRN, 2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76533WQ-2OMe)

The product SIRGT76533WQ-2OMe is a type of small interfering RNA (siRNA) that targets NGRN gene and regulates the expression of gene. The siRNA interferes with the expression of NGRN gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001033088.1
Alternative Names DSC92
Related Diseases Deafness
Purification HPLC
Target Gene
Gene ID 51335
Uniprot ID Q9NPE2
Sub Cat Target Species Modification Scale  
SIRGT78533WQ-2MOE NGRN Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79533WQ-LNA NGRN Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76533WQ-RB NGRN Human Ribo-modified Inquiry
SIRGT77533WQ-BB NGRN Human Backbone-modified Inquiry

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