siRNA, Anti-NKIRAS1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76536WQ-2OMe)

The product SIRGT76536WQ-2OMe is a type of small interfering RNA (siRNA) that targets NKIRAS1 gene and regulates the expression of gene. The siRNA interferes with the expression of NKIRAS1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_020345.3
Alternative Names KBRAS1; kappaB-Ras1
Related Diseases Diamond-Blackfan Anemia 12
Purification HPLC
Target Gene
Gene ID 28512
Uniprot ID Q9NYS0
Sub Cat Target Species Modification Scale  
SIRGT77536WQ-2F NKIRAS1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78536WQ-2MOE NKIRAS1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79536WQ-LNA NKIRAS1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76536WQ-RB NKIRAS1 Human Ribo-modified Inquiry
SIRGT77536WQ-BB NKIRAS1 Human Backbone-modified Inquiry

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