siRNA, Anti-NKX2-4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT71552WQ-2OMe)
The product SIRGT71552WQ-2OMe is a type of small interfering RNA (siRNA) that targets NKX2-4 gene and regulates the expression of gene. The siRNA interferes with the expression of NKX2-4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_033176.1 |
| Alternative Names | NKX2.4; NKX2D |
| Related Diseases | Diabetes Mellitus |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT72552WQ-2F | NKX2-4 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT73552WQ-2MOE | NKX2-4 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT74552WQ-LNA | NKX2-4 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT96142WQ-2OMe | Nkx2-4 | Mouse | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT97142WQ-2F | Nkx2-4 | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT98142WQ-2MOE | Nkx2-4 | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT99142WQ-LNA | Nkx2-4 | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT71552WQ-RB | NKX2-4 | Human | Ribo-modified | ||
| SIRGT72552WQ-BB | NKX2-4 | Human | Backbone-modified | ||
| SIRGT97142WQ-BB | Nkx2-4 | Mouse | Backbone-modified |
