siRNA, Anti-NKX2-6, 2'-F/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT57419WQ-2F)
The product SIRGT57419WQ-2F is a type of small interfering RNA (siRNA) that targets NKX2-6 gene and regulates the expression of gene. The siRNA interferes with the expression of NKX2-6 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001136271.2 |
| Alternative Names | CSX2; CTHM; NKX2F; NKX4-2 |
| Related Diseases | Conotruncal Heart Malformations |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT58419WQ-2MOE | NKX2-6 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT56419WQ-RB | NKX2-6 | Human | Ribo-modified | ||
| SIRGT57419WQ-BB | NKX2-6 | Human | Backbone-modified |