siRNA, Anti-NKX2-6, 2'-F/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT57419WQ-2F)

The product SIRGT57419WQ-2F is a type of small interfering RNA (siRNA) that targets NKX2-6 gene and regulates the expression of gene. The siRNA interferes with the expression of NKX2-6 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001136271.2
Alternative Names CSX2; CTHM; NKX2F; NKX4-2
Related Diseases Conotruncal Heart Malformations
Purification HPLC
Target Gene
Gene ID 137814
Uniprot ID A6NCS4
Sub Cat Target Species Modification Scale  
SIRGT58419WQ-2MOE NKX2-6 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT56419WQ-RB NKX2-6 Human Ribo-modified Inquiry
SIRGT57419WQ-BB NKX2-6 Human Backbone-modified Inquiry

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