siRNA, Anti-NKX2-8, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT71247WQ-2OMe)
The product SIRGT71247WQ-2OMe is a type of small interfering RNA (siRNA) that targets NKX2-8 gene and regulates the expression of gene. The siRNA interferes with the expression of NKX2-8 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_014360.3 |
| Alternative Names | NKX2.8; NKX2H; Nkx2-9 |
| Related Diseases | Bronchus Adenoma |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT72247WQ-2F | NKX2-8 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT73247WQ-2MOE | NKX2-8 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT74247WQ-LNA | NKX2-8 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT71247WQ-RB | NKX2-8 | Human | Ribo-modified | ||
| SIRGT72247WQ-BB | NKX2-8 | Human | Backbone-modified |
