siRNA, Anti-NKX6-2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT71553WQ-2OMe)

The product SIRGT71553WQ-2OMe is a type of small interfering RNA (siRNA) that targets NKX6-2 gene and regulates the expression of gene. The siRNA interferes with the expression of NKX6-2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_177400.2
Alternative Names GTX; NKX6.2; NKX6B; SPAX8
Related Diseases Spastic Ataxia 8
Purification HPLC
Target Gene
Gene ID 84504
Uniprot ID Q9C056
Sub Cat Target Species Modification Scale  
SIRGT72553WQ-2F NKX6-2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT73553WQ-2MOE NKX6-2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT74553WQ-LNA NKX6-2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT71553WQ-RB NKX6-2 Human Ribo-modified Inquiry
SIRGT72553WQ-BB NKX6-2 Human Backbone-modified Inquiry

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