siRNA, Anti-NTN5, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT56061WQ-2OMe)

The product SIRGT56061WQ-2OMe is a type of small interfering RNA (siRNA) that targets NTN5 gene and regulates the expression of gene. The siRNA interferes with the expression of NTN5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_145807.2
Related Diseases Retinitis Pigmentosa 22
Purification HPLC
Target Gene
Gene ID 126147
Uniprot ID Q8WTR8
Sub Cat Target Species Modification Scale  
SIRGT57061WQ-2F NTN5 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT101286WQ-2OMe Ntn5 Mouse 2ʹ-O-methyl (2'-OMe) Inquiry
SIRGT103286WQ-2MOE Ntn5 Mouse 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT104286WQ-LNA Ntn5 Mouse Locked Nucleic Acid (LNA) Inquiry
SIRGT101286WQ-RB Ntn5 Mouse Ribo-modified Inquiry
SIRGT57061WQ-BB NTN5 Human Backbone-modified Inquiry
SIRGT102286WQ-BB Ntn5 Mouse Backbone-modified Inquiry

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