siRNA, Anti-OR5M3, 2'-OMe/Ribo/Backbone-modified(CAT#: SIRGT61844WQ-2OMe)
The product SIRGT61844WQ-2OMe is a type of small interfering RNA (siRNA) that targets OR5M3 gene and regulates the expression of gene. The siRNA interferes with the expression of OR5M3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001004742.2 |
| Alternative Names | OR11-191 |
| Related Diseases | Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT61844WQ-RB | OR5M3 | Human | Ribo-modified | ||
| SIRGT62844WQ-BB | OR5M3 | Human | Backbone-modified |
