siRNA, Anti-ORMDL1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT52666WQ-2F)
The product SIRGT52666WQ-2F is a type of small interfering RNA (siRNA) that targets ORMDL1 gene and regulates the expression of gene. The siRNA interferes with the expression of ORMDL1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001128150.1 |
| Related Diseases | Retinitis Pigmentosa 26 |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT53666WQ-2MOE | ORMDL1 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT54666WQ-LNA | ORMDL1 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT96012WQ-2OMe | Ormdl1 | Mouse | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT97012WQ-2F | Ormdl1 | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT99012WQ-LNA | Ormdl1 | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT51666WQ-RB | ORMDL1 | Human | Ribo-modified | ||
| SIRGT96012WQ-RB | Ormdl1 | Mouse | Ribo-modified | ||
| SIRGT52666WQ-BB | ORMDL1 | Human | Backbone-modified | ||
| SIRGT97012WQ-BB | Ormdl1 | Mouse | Backbone-modified |
