siRNA, Anti-PADI3, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76582WQ-2OMe)

The product SIRGT76582WQ-2OMe is a type of small interfering RNA (siRNA) that targets PADI3 gene and regulates the expression of gene. The siRNA interferes with the expression of PADI3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_016233.2
Alternative Names PAD3; PDI3; UHS1
Related Diseases Uncombable Hair Syndrome 1
Purification HPLC
Target Gene
Gene ID 51702
Uniprot ID Q9ULW8
Sub Cat Target Species Modification Scale  
SIRGT77582WQ-2F PADI3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78582WQ-2MOE PADI3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79582WQ-LNA PADI3 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76582WQ-RB PADI3 Human Ribo-modified Inquiry
SIRGT77582WQ-BB PADI3 Human Backbone-modified Inquiry

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