siRNA, Anti-PAQR4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51958WQ-2OMe)

The product SIRGT51958WQ-2OMe is a type of small interfering RNA (siRNA) that targets PAQR4 gene and regulates the expression of gene. The siRNA interferes with the expression of PAQR4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001284511.1
Related Diseases Isolated Growth Hormone Deficiency, Type Ib
Purification HPLC
Target Gene
Gene ID 124222
Uniprot ID Q8N4S7
Sub Cat Target Species Modification Scale  
SIRGT52958WQ-2F PAQR4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53958WQ-2MOE PAQR4 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54958WQ-LNA PAQR4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51958WQ-RB PAQR4 Human Ribo-modified Inquiry
SIRGT52958WQ-BB PAQR4 Human Backbone-modified Inquiry

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