siRNA, Anti-PET117, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT71620WQ-2OMe)

The product SIRGT71620WQ-2OMe is a type of small interfering RNA (siRNA) that targets PET117 gene and regulates the expression of gene. The siRNA interferes with the expression of PET117 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001164811.1
Alternative Names CSRP2BP
Related Diseases Mitochondrial Complex Iv Deficiency
Purification HPLC
Target Gene
Gene ID 100303755
Uniprot ID Q6UWS5
Sub Cat Target Species Modification Scale  
SIRGT72620WQ-2F PET117 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT73620WQ-2MOE PET117 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT74620WQ-LNA PET117 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT71620WQ-RB PET117 Human Ribo-modified Inquiry
SIRGT72620WQ-BB PET117 Human Backbone-modified Inquiry

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