siRNA, Anti-PIGM, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT53614WQ-2MOE)
The product SIRGT53614WQ-2MOE is a type of small interfering RNA (siRNA) that targets PIGM gene and regulates the expression of gene. The siRNA interferes with the expression of PIGM gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2'-O-methoxyethyl (2'-MOE) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_145167.2 |
| Alternative Names | GPI-MT-I |
| Related Diseases | Glycosylphosphatidylinositol Biosynthesis Defect 1 |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT51614WQ-2OMe | PIGM | Human | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT52614WQ-2F | PIGM | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT54614WQ-LNA | PIGM | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT51614WQ-RB | PIGM | Human | Ribo-modified | ||
| SIRGT52614WQ-BB | PIGM | Human | Backbone-modified |