siRNA, Anti-PNMA6A, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51171WQ-2OMe)

The product SIRGT51171WQ-2OMe is a type of small interfering RNA (siRNA) that targets PNMA6A gene and regulates the expression of gene. The siRNA interferes with the expression of PNMA6A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_032882.5
Alternative Names MA6; PNMA6; PNMA6C
Related Diseases Spinal Muscular Atrophy
Purification HPLC
Target Gene
Gene ID 84968
Uniprot ID P0CW24
Sub Cat Target Species Modification Scale  
SIRGT52171WQ-2F PNMA6A Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53171WQ-2MOE PNMA6A Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54171WQ-LNA PNMA6A Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51171WQ-RB PNMA6A Human Ribo-modified Inquiry
SIRGT52171WQ-BB PNMA6A Human Backbone-modified Inquiry

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