siRNA, Anti-PNPLA8, 2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76629WQ-2OMe)

The product SIRGT76629WQ-2OMe is a type of small interfering RNA (siRNA) that targets PNPLA8 gene and regulates the expression of gene. The siRNA interferes with the expression of PNPLA8 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_015723.4
Alternative Names IPLA2-2; IPLA2G; MMLA; PNPLA-gamma; iPLA2gamma
Related Diseases Mitochondrial Myopathy
Purification HPLC
Target Gene
Gene ID 50640
Uniprot ID Q9NP80
Sub Cat Target Species Modification Scale  
SIRGT78629WQ-2MOE PNPLA8 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79629WQ-LNA PNPLA8 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76629WQ-RB PNPLA8 Human Ribo-modified Inquiry
SIRGT77629WQ-BB PNPLA8 Human Backbone-modified Inquiry

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