siRNA, Anti-PPHLN1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT77638WQ-2F)
The product SIRGT77638WQ-2F is a type of small interfering RNA (siRNA) that targets PPHLN1 gene and regulates the expression gene. The siRNA interferes with the expression PPHLN1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_201515.1 |
| Alternative Names | CR; HSPC206; HSPC232 |
| Related Diseases | Ichthyosis |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT78638WQ-2MOE | PPHLN1 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT79638WQ-LNA | PPHLN1 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT91797WQ-2OMe | Pphln1 | Mouse | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT92797WQ-2F | Pphln1 | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT93797WQ-2MOE | Pphln1 | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT94797WQ-LNA | Pphln1 | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT76638WQ-RB | PPHLN1 | Human | Ribo-modified | ||
| SIRGT91797WQ-RB | Pphln1 | Mouse | Ribo-modified | ||
| SIRGT77638WQ-BB | PPHLN1 | Human | Backbone-modified | ||
| SIRGT92797WQ-BB | Pphln1 | Mouse | Backbone-modified |
