siRNA, Anti-PPM1N, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT56681WQ-2OMe)
The product SIRGT56681WQ-2OMe is a type of small interfering RNA (siRNA) that targets PPM1N gene and regulates the expression of gene. The siRNA interferes with the expression of PPM1N gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001080401.1 |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT57681WQ-2F | PPM1N | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT58681WQ-2MOE | PPM1N | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT59681WQ-LNA | PPM1N | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT96598WQ-2OMe | Ppm1n | Mouse | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT97598WQ-2F | Ppm1n | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT98598WQ-2MOE | Ppm1n | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT99598WQ-LNA | Ppm1n | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT56681WQ-RB | PPM1N | Human | Ribo-modified | ||
| SIRGT96598WQ-RB | Ppm1n | Mouse | Ribo-modified | ||
| SIRGT57681WQ-BB | PPM1N | Human | Backbone-modified | ||
| SIRGT97598WQ-BB | Ppm1n | Mouse | Backbone-modified |
