siRNA, Anti-PPP1R15B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51131WQ-RB)
The product SIRGT51131WQ-RB is a type of small interfering RNA (siRNA) that targets PPP1R15B gene and regulates the expression of gene. The siRNA interferes with the expression of PPP1R15B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with Ribo modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_032833.4 |
| Alternative Names | CREP; MSSGM2 |
| Related Diseases | Microcephaly |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT52131WQ-2F | PPP1R15B | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT53131WQ-2MOE | PPP1R15B | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT54131WQ-LNA | PPP1R15B | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT86132WQ-2OMe | Ppp1r15b | Mouse | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT87132WQ-2F | Ppp1r15b | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT89132WQ-LNA | Ppp1r15b | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT86132WQ-RB | Ppp1r15b | Mouse | Ribo-modified | ||
| SIRGT52131WQ-BB | PPP1R15B | Human | Backbone-modified | ||
| SIRGT87132WQ-BB | Ppp1r15b | Mouse | Backbone-modified |
