siRNA, Anti-PPP1R42, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT66455WQ-2OMe)

The product SIRGT66455WQ-2OMe is a type of small interfering RNA (siRNA) that targets PPP1R42 gene and regulates the expression of gene. The siRNA interferes with the expression of PPP1R42 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001013626.3
Alternative Names LRRC67; TLLR; TLRR; dtr
Related Diseases Rectosigmoid Cancer
Purification HPLC
Target Gene
Gene ID 286187
Uniprot ID Q7Z4L9
Sub Cat Target Species Modification Scale  
SIRGT67455WQ-2F PPP1R42 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT68455WQ-2MOE PPP1R42 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT69455WQ-LNA PPP1R42 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT66455WQ-RB PPP1R42 Human Ribo-modified Inquiry
SIRGT67455WQ-BB PPP1R42 Human Backbone-modified Inquiry

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