siRNA, Anti-RDH12, 2'-F/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT57570WQ-2F)

The product SIRGT57570WQ-2F is a type of small interfering RNA (siRNA) that targets RDH12 gene and regulates the expression of gene. The siRNA interferes with the expression of RDH12 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_152443.2
Alternative Names LCA13; RP53; SDR7C2
Related Diseases Leber Congenital Amaurosis 13
Purification HPLC
Target Gene
Gene ID 145226
Uniprot ID Q96NR8
Sub Cat Target Species Modification Scale  
SIRGT58570WQ-2MOE RDH12 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT59570WQ-LNA RDH12 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT56570WQ-RB RDH12 Human Ribo-modified Inquiry
SIRGT57570WQ-BB RDH12 Human Backbone-modified Inquiry

Related Products