siRNA, Anti-RHEX, 2'-OMe/Ribo/Backbone-modified(CAT#: SIRGT66448WQ-2OMe)

The product SIRGT66448WQ-2OMe is a type of small interfering RNA (siRNA) that targets RHEX gene and regulates the expression of gene. The siRNA interferes with the expression of RHEX gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001007544.3
Alternative Names C1orf186
Related Diseases Fuchs' Endothelial Dystrophy
Purification HPLC
Target Gene
Gene ID 440712
Uniprot ID Q6ZWK4
Sub Cat Target Species Modification Scale  
SIRGT66448WQ-RB RHEX Human Ribo-modified Inquiry
SIRGT67448WQ-BB RHEX Human Backbone-modified Inquiry

Related Products