siRNA, Anti-RPEL1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT66491WQ-2OMe)

The product SIRGT66491WQ-2OMe is a type of small interfering RNA (siRNA) that targets RPEL1 gene and regulates the expression of gene. The siRNA interferes with the expression of RPEL1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001143909.1
Related Diseases Oliver-Mcfarlane Syndrome
Purification HPLC
Target Gene
Gene ID 729020
Uniprot ID Q2QD12
Sub Cat Target Species Modification Scale  
SIRGT67491WQ-2F RPEL1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT68491WQ-2MOE RPEL1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT69491WQ-LNA RPEL1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT66491WQ-RB RPEL1 Human Ribo-modified Inquiry
SIRGT67491WQ-BB RPEL1 Human Backbone-modified Inquiry

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