siRNA, Anti-SELENOI, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51264WQ-2OMe)

The product SIRGT51264WQ-2OMe is a type of small interfering RNA (siRNA) that targets SELENOI gene and regulates the expression of gene. The siRNA interferes with the expression of SELENOI gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_033505.3
Alternative Names EPT1; SELI; SEPI
Related Diseases Spastic Paraplegia 81
Purification HPLC
Target Gene
Gene ID 85465
Uniprot ID Q9C0D9
Sub Cat Target Species Modification Scale  
SIRGT52264WQ-2F SELENOI Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53264WQ-2MOE SELENOI Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54264WQ-LNA SELENOI Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51264WQ-RB SELENOI Human Ribo-modified Inquiry
SIRGT52264WQ-BB SELENOI Human Backbone-modified Inquiry

Related Products