siRNA, Anti-SEPTIN8, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT36748WQ-2OMe)
The product SIRGT36748WQ-2OMe is a type of small interfering RNA (siRNA) that targets 8-Sep gene and regulates the expression of gene. The siRNA interferes with the expression of 8-Sep gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001098811.1 |
| Alternative Names | SEP2 |
| Related Diseases | Sexual Disorder and Impotence |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT37748WQ-2F | SEPTIN8 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT38748WQ-2MOE | SEPTIN8 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT39748WQ-LNA | SEPTIN8 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT36748WQ-RB | SEPTIN8 | Human | Ribo-modified | ||
| SIRGT37748WQ-BB | SEPTIN8 | Human | Backbone-modified |