siRNA, Anti-SMR3A, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT71361WQ-2OMe)

The product SIRGT71361WQ-2OMe is a type of small interfering RNA (siRNA) that targets SMR3A gene and regulates the expression of gene. The siRNA interferes with the expression of SMR3A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_012390.3
Alternative Names P-B1; PBI; PRL5; PROL5
Related Diseases Scheuermann Disease
Purification HPLC
Target Gene
Gene ID 26952
Uniprot ID Q99954
Sub Cat Target Species Modification Scale  
SIRGT72361WQ-2F SMR3A Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT73361WQ-2MOE SMR3A Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT74361WQ-LNA SMR3A Human Locked Nucleic Acid (LNA) Inquiry
SIRGT71361WQ-RB SMR3A Human Ribo-modified Inquiry
SIRGT72361WQ-BB SMR3A Human Backbone-modified Inquiry

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