siRNA, Anti-SP140L, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51622WQ-2OMe)

The product SIRGT51622WQ-2OMe is a type of small interfering RNA (siRNA) that targets SP140L gene and regulates the expression of gene. The siRNA interferes with the expression of SP140L gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001308162.2
Purification HPLC
Target Gene
Gene ID 93349
Uniprot ID Q9H930
Sub Cat Target Species Modification Scale  
SIRGT52622WQ-2F SP140L Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53622WQ-2MOE SP140L Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54622WQ-LNA SP140L Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51622WQ-RB SP140L Human Ribo-modified Inquiry
SIRGT52622WQ-BB SP140L Human Backbone-modified Inquiry

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