siRNA, Anti-SPG21, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76789WQ-2OMe)

The product SIRGT76789WQ-2OMe is a type of small interfering RNA (siRNA) that targets SPG21 gene and regulates the expression of gene. The siRNA interferes with the expression of SPG21 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_016630.6
Alternative Names ACP33; BM-019; GL010; MAST
Related Diseases Mast Syndrome
Purification HPLC
Target Gene
Gene ID 51324
Uniprot ID Q9NZD8
Sub Cat Target Species Modification Scale  
SIRGT77789WQ-2F SPG21 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78789WQ-2MOE SPG21 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79789WQ-LNA SPG21 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76789WQ-RB SPG21 Human Ribo-modified Inquiry
SIRGT77789WQ-BB SPG21 Human Backbone-modified Inquiry

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