siRNA, Anti-SPPL2C, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT62738WQ-2F)
The product SIRGT62738WQ-2F is a type of small interfering RNA (siRNA) that targets SPPL2C gene and regulates the expression of gene. The siRNA interferes with the expression of SPPL2C gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_175882.2 |
| Alternative Names | IMP5 |
| Related Diseases | Chromosome 17Q21.31 Duplication Syndrome |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT63738WQ-2MOE | SPPL2C | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT64738WQ-LNA | SPPL2C | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT101033WQ-2OMe | Sppl2c | Mouse | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT103033WQ-2MOE | Sppl2c | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT104033WQ-LNA | Sppl2c | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT61738WQ-RB | SPPL2C | Human | Ribo-modified | ||
| SIRGT101033WQ-RB | Sppl2c | Mouse | Ribo-modified | ||
| SIRGT62738WQ-BB | SPPL2C | Human | Backbone-modified | ||
| SIRGT102033WQ-BB | Sppl2c | Mouse | Backbone-modified |
