siRNA, Anti-STON1-GTF2A1L, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT71808WQ-2OMe)
The product SIRGT71808WQ-2OMe is a type of small interfering RNA (siRNA) that targets STON1-GTF2A1L gene and regulates the expression of gene. The siRNA interferes with the expression of STON1-GTF2A1L gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001198593.1 |
| Alternative Names | SALF |
| Related Diseases | Leydig Cell Hypoplasia |
| Purification | HPLC |
| Target Gene | |
|---|---|
| Gene ID | 286749 |
| Uniprot ID | A0A0A6YYG5 |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT72808WQ-2F | STON1-GTF2A1L | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT73808WQ-2MOE | STON1-GTF2A1L | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT74808WQ-LNA | STON1-GTF2A1L | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT71808WQ-RB | STON1-GTF2A1L | Human | Ribo-modified | ||
| SIRGT72808WQ-BB | STON1-GTF2A1L | Human | Backbone-modified |