siRNA, Anti-SUFU, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76813WQ-2OMe)

The product SIRGT76813WQ-2OMe is a type of small interfering RNA (siRNA) that targets SUFU gene and regulates the expression of gene. The siRNA interferes with the expression of SUFU gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_016169.3
Alternative Names JBTS32; PRO1280; SUFUH; SUFUXL
Related Diseases Joubert Syndrome 32
Purification HPLC
Target Gene
Gene ID 51684
Uniprot ID Q9UMX1
Sub Cat Target Species Modification Scale  
SIRGT77813WQ-2F SUFU Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78813WQ-2MOE SUFU Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79813WQ-LNA SUFU Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76813WQ-RB SUFU Human Ribo-modified Inquiry
SIRGT77813WQ-BB SUFU Human Backbone-modified Inquiry

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