siRNA, Anti-SUMF1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT71814WQ-2OMe)

The product SIRGT71814WQ-2OMe is a type of small interfering RNA (siRNA) that targets SUMF1 gene and regulates the expression of gene. The siRNA interferes with the expression of SUMF1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001164674.1
Alternative Names AAPA3037; FGE; UNQ3037
Related Diseases Multiple Sulfatase Deficiency
Purification HPLC
Target Gene
Gene ID 285362
Uniprot ID Q8NBK3
Sub Cat Target Species Modification Scale  
SIRGT72814WQ-2F SUMF1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT73814WQ-2MOE SUMF1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT74814WQ-LNA SUMF1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT71814WQ-RB SUMF1 Human Ribo-modified Inquiry
SIRGT72814WQ-BB SUMF1 Human Backbone-modified Inquiry

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