siRNA, Anti-TLX3, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76854WQ-2OMe)

The product SIRGT76854WQ-2OMe is a type of small interfering RNA (siRNA) that targets TLX3 gene and regulates the expression of gene. The siRNA interferes with the expression of TLX3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_021025.3
Alternative Names HOX11L2; RNX
Related Diseases Precursor T-Cell Acute Lymphoblastic Leukemia
Purification HPLC
Target Gene
Gene ID 30012
Uniprot ID O43711
Sub Cat Target Species Modification Scale  
SIRGT77854WQ-2F TLX3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78854WQ-2MOE TLX3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79854WQ-LNA TLX3 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76854WQ-RB TLX3 Human Ribo-modified Inquiry
SIRGT77854WQ-BB TLX3 Human Backbone-modified Inquiry

Related Products